Louise is an insecure big-haired brainy high school-er with an equally nerdy and enthusiastic best friend Polly. After a series of embarrassing events and bad luck, Louise finds herself at the palm reading parlor of Serena, a witch who reveals that Louise is also a witch who will gain powers on her impending 16th birthday. The next week, once she has turned 16, Louise finds this to be the case and accidentally turns her brother into a dog.