Cleo Eastman is a teen girl who is always living in her older popular sister Molly's shadows, her sister is the most popular girl at school and recognized by everyone, but she is hardly seen by anyone else. While working on a science project High School student Cleo accidentally creates a vapor that turns a moth invisible. But that's not the only thing she turns invisible she finds out she turned her older sister invisible. With her sister invisible and only hours to find a cure Cleo must use her friends and her skills to find a cure for her invisible sister.